Mironov Vladimir

M.D., Ph.D., Head of Research at the Laboratory for Biotechnological Research of 3D Bioprinting Solutions phone: +7 (499) 769-50-18 info@bioprinting.ru In 1977, graduated from the department of general medicine at the Ivanovo State Medical University (currently renamed as academy). In 1980, awarded the Candidate of Medical Sciences academic degree specializing in Histology and Embryology from 2nd Moscow State Medical Institute (currently renamed as N.I. Pirogov Russian National Research Medical University). 1980-1985: Assistant Professor at the Histology and Embryology Department of the Ivanovo State Medical University (currently renamed as academy). 1985-1990: Senior researcher at the Ivanovo Research Institute of Maternity and Childhood. 1990-1991: Senior researcher at the Research Institute of Morphology of Russian Academy of Medical Sciences. 1991: Moved to Germany to the RWTH Aachen University, where he continued his education, and in 1992, he moved to the Max Planck Institute of Psychiatry. In 1993, V.A. Mironov was invited for a post-doctoral course to the Medical University of South Carolina, USA. From 2000, he worked as assistant professor and from 2005 -- as associate professor at the Department of Regenerative Medicine and Cell Biology. Simultaneously, he performed as assistant professor at the Department of Cell Biology and Anatomy. At the same time, V.A. Mironov headed the Advanced Tissue Biofabrication Center (which he created) at the Medical University of South Carolina, USA. Currently, V.A. Mironov is Professor at the Virginia Commonwealth University, Department of Chemical and Life Science Engineering, works at the Center for information Technology Renato Archer, Campinas, State of São Paulo and at the national research university, MIET, and is Head of Research of the 3D Bioprinting Solutions company. Mironov is the author (collective authorship) of the following patents: 1.Synthetic vascular tissue and method of forming same. US patent 8124001, February 28, 2012 (fabrication of nanofiber vascular grafts). 2.Self-assembling cell aggregates and methods of making engineered tissue. US patent 8241905, August 14, 2012 (apparatus for the fabrication of tissue spheroids). 3.Reversible gelling culture media for in-vitro cell culture in three-dimensional matrices. US patent 6103528, August 15, 2000 (hydrogel for obtaining 3D tissue constructs). V.A. Mironov is the author of the first publication on organ printing Organ printing: computer-aided jet-based 3D tissue engineering. Mironov V, Boland T, Trusk T, Forgacs G, Markwald RR. Trends Biotechnol. 2003 Apr; 21(4):157-61. V.A. Mironov possesses a profound experience in managing multidisciplinary research. 1.German Academic Exchange Service (DAAD) Fellowship, RWTH, Aachen, Germany, 1991. 2.NIH Forgarty Fellowship, Case Western Reserve University, Clevelend, Ohio, USA, 1992. 3.Association of USA Publishers Award as Invited Editor of the Best Journal Issue of The Year, 2000. 4.Finalist of The World Technology Award, 2004. 5.Tan ChenTuan Fellowship. Nanyang Technological University, Singapore, 2008. 6.FAPESP (San Paulo State Research Funding Organization) Visiting Professor 12 months Fellowship at Renato Archer Centro de Tecnologia da Informacao, Campinas, Brasil 2012. Selected publications 1.Torgersen J, Ovsianikov A, Mironov V, Pucher N, Qin X, Li Z, Cicha K, Machacek T, Liska R, Jantsch V, Stampfl J. Photo-sensitive hydrogels for three-dimensional laser microfabrication in the presence of whole organisms. J Biomed Opt. 2012 Oct 1;17(10):105008. 2.Ovsianikov A, Mironov V, Stampfl J, Liska R. Engineering 3D cell-culture matrices: multiphoton processing technologies for biological & tissue engineering applications.Expert Rev Med Devices. 2012 Sep 3.Yang X, Mironov V, Wang Q. Modeling fusion of cellular aggregates in biofabrication using phase field theories. J Theor Biol. 2012 Jun 21;303:110-8. Epub 2012 Mar 13. 4.Mironov V, Kasyanov V, Markwald RR. Organ printing: from bioprinter to organ biofabrication line. Curr Opin Biotechnol. 2011 Oct;22(5):667-73. 5.Mehesz AN, Brown J, Hajdu Z, Beaver W, da Silva JV, Visconti RP, Markwald RR, Mironov V. Scalable robotic biofabrication of tissue spheroids. Biofabrication. 2011 Jun;3(2):025002. Epub 2011 May 12. 6.Hajdu Z, Mironov V, Mehesz AN, Norris RA, Markwald RR, Visconti RP. Tissue spheroid fusion-based in vitro screening assays for analysis of tissue maturation. J Tissue Eng Regen Med. 2010 Dec;4(8):659-64. doi: 10.1002/term.291. 7.Visconti RP, Kasyanov V, Gentile C, Zhang J, Markwald RR, Mironov V. Towards organ printing: engineering an intra-organ branched vascular tree. Expert Opin Biol Ther. 2010 Mar;10(3):409-20. Review. 8.Guillemot F, Mironov V, Nakamura M. Bioprinting is coming of age: Report from the International Conference on Bioprinting and Biofabrication in Bordeaux (3B'09).Biofabrication. 2010 Mar;2(1):010201. Epub 2010 Mar 11. 9.Mironov V, Trusk T, Kasyanov V, Little S, Swaja R, Markwald R. Biofabrication: a 21st century manufacturing paradigm. Biofabrication. 2009 Jun;1(2):022001. 10.Mironov V, Kasyanov V. Emergence of clinical vascular tissue engineering. Lancet. 2009 Apr 25;373(9673):1402-4. 11.Mironov V, Visconti RP, Kasyanov V, Forgacs G, Drake CJ, Markwald RR. Organ printing: tissue spheroids as building blocks. Biomaterials. 2009 Apr;30(12):2164-74. 12.Neagu A, Mironov V, Kosztin I, Barz B, Neagu M, Moreno-Rodriguez RA, Markwald RR, Forgacs G. Computational modeling of epithelial-mesenchymal transformations. Biosystems. 2010 Apr;100(1):23-30. Epub 2009 Dec 31. 13.Mironov V, Kasyanov V, Markwald RR Nanotechnology in vascular tissue engineering: from nanoscaffolding towards rapid vessel biofabrication.. Trends Biotechnol. 2008 Jun;26(6):338-44. 14. Mironov V, Kasyanov V, Drake C, Markwald RR. Organ printing: promises and challenges. Regen Med. 2008 Jan;3(1):93-103. 15.Gentile C, Fleming PA, Mironov V, Argraves KM, Argraves WS, Drake CJ. VEGF-mediated fusion in the generation of uniluminal vascular spheroids. Dev Dyn. 2008 Oct;237(10):2918-25. 16.Jakab K, Damon B, Marga F, Doaga O, Mironov V, Kosztin I, Markwald R, Forgacs G. Relating cell and tissue mechanics: implications and applications. Dev Dyn. 2008 Sep;237(9):2438-49. 17.Mironov V. Toward human organ printing: Charleston Bioprinting Symposium. ASAIO J. 2006 Nov-Dec;52(6):e27-30. 18.Mironov V, Drake C, Wen X. Research project: Charleston Bioengineered Kidney Project. Biotechnol J. 2006 Sep;1(9):903-5. 19.Mironov V, Kasyanov VA, Yost MJ, Visconti R, Twal W, Trusk T, Wen X, Ozolanta I, Kadishs A, Prestwich GD, Terracio L, Markwald RR. Cardiovascular tissue engineering I. Perfusion bioreactors: a review. J Long Term Eff Med Implants. 2006;16(2):111-30. Review. 20.Mironov V, Reis N, Derby B. Review: bioprinting: a beginning.Tissue Eng. 2006 Apr;12(4):631-4. Review. 21.Jakab K, Neagu A, Mironov V, Forgacs G. Organ printing: fiction or science. Biorheology. 2004;41(3-4):371-5. 22.Mironov V, Boland T, Trusk T, Forgacs G, Markwald RR. Organ printing: computer-aided jet-based 3D tissue engineering. Trends Biotechnol. 2003 Apr;21(4):157-6 23.Mironov V, Markwald RR. Anatomy of tissue engineering. Anat Rec. 2001 Aug 1;263(4):335 24.Mironov V, Hesuani Y, Pereira F, Parfenov V, Koudan E, Mitryashkin A, Replyanski N, Kasyanov V, Knyazeva A, Bulanova E, Design and implementation of novel multifunctional 3D bioprinter. 3D Printing and Additive Manufacturing. 2015-0040.R1 25.Е.В. Кудан, Ф. Д.А.С. Перейра, В.A. Парфенов, В.А. Касьянов, Ю.Д. Хесуани, Е.А. Буланова, В.А. Миронов. Распластывание тканевых сфероидов, сформированных из первичных фибробластов человека, на поверхности микроволокнистого электроспиннингового полиуретанового матрикса (сканирующее электронно-микроскопическое исследование). Морфология, №6, 2015 26.Vladimir Mironov, Yusef D. Khesuani, Elena A. Bulanova, Elizaveta V. Koudan, Vladislav A. Parfenov, Anastasia D. Knyazeva, Alexander N. Mitryashkin, Nikita Replyanski, Vladimir A. Kasyanov, Frederico Pereira D.A.S. Patterning of tissue spheroids biofabricated from human fibroblasts on the surface of electrospun polyurethane matrix using 3D bioprinter. International Journal of Bioprinting, №1, 2016